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化合物简介
Genistin is an isoflavone found in a number of dietary plants like soy and kudzu. It was first isolated in 1931 from the 90% methanol extract of a soybean meal, when it was found that hydrolysis with hydrochloric acid produced 1 mole each of genistein and glucose. Chemically it is the 7-O-beta-D-glucoside form of genistein and is the predominant form of the isoflavone naturally occurring in plants. In fact Studies in the 1970s revealed that 99% of the isoflavonoid compounds in soy are present as their glucosides. The glucosides are converted by digestive enzymes in the digestive system to exert their biological effects. Genistin is also converted to a more familiar genistein, thus, the biological activities including antiatherosclerotic, estrogenic and anticancer effects are analogous.
基本信息
CAS:529-59-9
中文别名:4,5,7-三羟异黄酮-7-糖苷;染料木甙;4\',5,7-三羟异黄酮-7-糖苷;
英文别名:Soybean Extract;GLUCOSYL-7-GENISTEIN;4\',5,7-Trihydroxyisoflavone 7-glucoside;Genistoside;genistein 7-O-glucoside;Genistein 7-glucoside;GENISTEIN-7-GLUCOSIDE;genistine;4\',5,7-trihydroxyisoflavone-7-D-glucoside;Genistein-7-O-β-D-glucopyranoside;genistein 7-O-beta-D-glucoside;Genistin;
分子式:C21H20O10
分子量:432.378
精确质量:432.106
Psa:170.05
Logp:0.0499
中文别名:4,5,7-三羟异黄酮-7-糖苷;染料木甙;4\',5,7-三羟异黄酮-7-糖苷;
英文别名:Soybean Extract;GLUCOSYL-7-GENISTEIN;4\',5,7-Trihydroxyisoflavone 7-glucoside;Genistoside;genistein 7-O-glucoside;Genistein 7-glucoside;GENISTEIN-7-GLUCOSIDE;genistine;4\',5,7-trihydroxyisoflavone-7-D-glucoside;Genistein-7-O-β-D-glucopyranoside;genistein 7-O-beta-D-glucoside;Genistin;
分子式:C21H20O10
分子量:432.378
精确质量:432.106
Psa:170.05
Logp:0.0499
编号系统
UNII:1POG3SCN5T
物化性质
外观与性状:无色晶体
密度:1.642 g/cm3
沸点:788.9ºC at 760 mmHg
熔点:254ºC
闪点:280.7ºC
折射率:1.717
储存条件:-20ºC
密度:1.642 g/cm3
沸点:788.9ºC at 760 mmHg
熔点:254ºC
闪点:280.7ºC
折射率:1.717
储存条件:-20ºC
安全信息
RTECS号:DJ3093000
安全说明:S22-S24/25
WGK Germany:3
安全说明:S22-S24/25
WGK Germany:3
生产方法及用途
生产方法
染料木苷植物来源 染料木苷药理作用,有雌激素活性,服后能增加雄性和切除卵巢的仓鼠的食欲和体重。抗肿瘤和性激素。
用途
染料木苷药理作用,有雌激素活性,服后能增加雄性和切除卵巢的仓鼠的食欲和体重。抗肿瘤和性激素。
染料木苷植物来源 染料木苷药理作用,有雌激素活性,服后能增加雄性和切除卵巢的仓鼠的食欲和体重。抗肿瘤和性激素。
用途
染料木苷药理作用,有雌激素活性,服后能增加雄性和切除卵巢的仓鼠的食欲和体重。抗肿瘤和性激素。
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR
