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化合物简介
Dimenhydrinate (marketed as Dramamine, Gravol and many other brand names) is an over-the-counter antiemetic used for the treatment of the symptoms of motion sickness. It is most commonly prepared as tablets, although it is also available in liquid form and in suppositories. Dimenhydrinate is a combination of two drugs: diphenhydramine and 8-chlorotheophylline.
基本信息
CAS:523-87-5
中文别名:1,3-二甲基-8-氯-3,7-二氢-1H-嘌呤-2,6-二酮 N,N-二甲基-2-(二苯基甲氧基)乙胺;1,3-二甲基-8氯-3,7-二氢-1H-嘌呤,6二酮-N,N-二甲基-2-(二苯基甲氧基)乙胺盐;
英文别名:N-(2-Diphenylmethoxyethyl)-N,N-dimethylammonium 8-chlorotheophyllinate;emes;8-chloro-1,3-dimethyl-3,7-dihydro-purine-2,6-dione,compound with (2-benzhydryloxy-ethyl)-dimethyl-amine;vomexa;faston;epha;gravol;amosyt;Dimenhydrinate;emedyl;dramyl;8-Chlor-1,3-dimethyl-3,7-dihydro-purin-2,6-dion,Verbindung mit (2-Benzhydryloxy-aethyl)-dimethyl-amin;Dimenhydrinase;dromyl;DiMate;
分子式:C24H28ClN5O3
分子量:469.964
精确质量:469.188
Psa:85.15
Logp:2.9679
中文别名:1,3-二甲基-8-氯-3,7-二氢-1H-嘌呤-2,6-二酮 N,N-二甲基-2-(二苯基甲氧基)乙胺;1,3-二甲基-8氯-3,7-二氢-1H-嘌呤,6二酮-N,N-二甲基-2-(二苯基甲氧基)乙胺盐;
英文别名:N-(2-Diphenylmethoxyethyl)-N,N-dimethylammonium 8-chlorotheophyllinate;emes;8-chloro-1,3-dimethyl-3,7-dihydro-purine-2,6-dione,compound with (2-benzhydryloxy-ethyl)-dimethyl-amine;vomexa;faston;epha;gravol;amosyt;Dimenhydrinate;emedyl;dramyl;8-Chlor-1,3-dimethyl-3,7-dihydro-purin-2,6-dion,Verbindung mit (2-Benzhydryloxy-aethyl)-dimethyl-amin;Dimenhydrinase;dromyl;DiMate;
分子式:C24H28ClN5O3
分子量:469.964
精确质量:469.188
Psa:85.15
Logp:2.9679
编号系统
UNII:JB937PER5C
物化性质
外观与性状:结晶白色粉末
沸点:343.7ºC at 760 mmHg
熔点:102-107ºC
闪点:101.5ºC
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
沸点:343.7ºC at 760 mmHg
熔点:102-107ºC
闪点:101.5ºC
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
安全信息
安全说明:S22; S26; S36/37/39; S53
危险类别码:R22
海关编码:2933990090
危险品标志:Xn
危险类别码:R22
海关编码:2933990090
危险品标志:Xn
生产方法及用途
用途
用于防治晕动病,如晕车,晕船,晕机所致的恶心,呕吐。
用于防治晕动病,如晕车,晕船,晕机所致的恶心,呕吐。
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

IR : KBr disc

IR : nujol mull
