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化合物简介
Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name, but also the ber tree (Ziziphus mauritiana), selfheal (Prunella vulgaris), the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas, a member of the persimmon family, Tetracera boiviniana, the jambul (Syzygium formosanum), flowering quince (Pseudocydonia sinensis, former Chaenomeles sinensis KOEHNE), rosemary, and Pulsatilla chinensis.
基本信息
CAS:472-15-1
中文别名:桦木酸;樺酸;香柠檬烯;白桦酯酸;
英文别名:BETULIC ACID;Betulinic Acid;Gratiolone;Betulinic acid;MAIRIN;Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-;Melaleucin;ALS-357;Platanol;3β-Hydroxy-20(29)-lupaene-28-oic Acid;Betulinic;
分子式:C30H48O3
分子量:456.7
精确质量:456.36
Psa:57.53
Logp:7.0895
中文别名:桦木酸;樺酸;香柠檬烯;白桦酯酸;
英文别名:BETULIC ACID;Betulinic Acid;Gratiolone;Betulinic acid;MAIRIN;Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-;Melaleucin;ALS-357;Platanol;3β-Hydroxy-20(29)-lupaene-28-oic Acid;Betulinic;
分子式:C30H48O3
分子量:456.7
精确质量:456.36
Psa:57.53
Logp:7.0895
编号系统
MDL号:MFCD00009619
物化性质
外观与性状:白色结晶粉末
密度:1.065 g/cm3
沸点:550ºC at 760 mmHg
熔点:295-298°C (dec.)(lit.)
闪点:300.5ºC
折射率:7.8 ° (C=0.9, Pyridine)
储存条件:Store at +4ºC
蒸汽压:2.67E-14mmHg at 25°C
密度:1.065 g/cm3
沸点:550ºC at 760 mmHg
熔点:295-298°C (dec.)(lit.)
闪点:300.5ºC
折射率:7.8 ° (C=0.9, Pyridine)
储存条件:Store at +4ºC
蒸汽压:2.67E-14mmHg at 25°C
安全信息
WGK Germany:3
海关编码:2942000000
危险品标志:Xi
海关编码:2942000000
危险品标志:Xi
生产方法及用途
合成路线
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参考文献
Barthel, Alexander; Stark, Sebastian; Csuk, Rene Tetrahedron, 2008 , vol. 64, # 39 p. 9225 - 9229
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