Doxylamine is a first-generation antihistamine, first reported in 1949. It can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. Doxylamine is also used in combination with the analgesics paracetamol (acetaminophen) and codeine as an analgesic/calmative preparation, and is prescribed in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women. Its fetal safety is “A” in Briggs’ Reference Guide to Foetal and Neonatal Risk.

CAS：469-21-6
中文别名：抗敏安;
英文别名：Dossilamina;Doxylamine;doxilamina;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine;Doxilminio;Doxylaminum;
分子式：C17H22N2O
分子量：270.369
精确质量：270.173
Psa：25.36
Logp：2.9233

UNII：95QB77JKPL

密度：1.043 g/cm3
沸点：364.9ºC at 760 mmHg
闪点：174.5ºC