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化合物简介
Naloxone is a specific opioid antagonist. Narcotic antagonist.
基本信息
CAS：465-65-6
中文别名：(5alpha)-3,14-二羟基-17-丙-2-烯-1-基-4,5-环氧吗啡烷-6-酮;(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one;
英文别名：Narcon;Narcanti;Nalone;[14C]-Naloxone;(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;Naloxone;[3H]-Naloxone;EN 1530 base;Narcan;Naloxona;n-Allylnoroxymorphone;Naloxonum;l-Naloxone;
分子式：C19H21NO4
分子量：327.374
精确质量：327.147
Psa：70.0
Logp：1.2393
中文别名：(5alpha)-3,14-二羟基-17-丙-2-烯-1-基-4,5-环氧吗啡烷-6-酮;(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one;
英文别名：Narcon;Narcanti;Nalone;[14C]-Naloxone;(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;Naloxone;[3H]-Naloxone;EN 1530 base;Narcan;Naloxona;n-Allylnoroxymorphone;Naloxonum;l-Naloxone;
分子式：C19H21NO4
分子量：327.374
精确质量：327.147
Psa：70.0
Logp：1.2393
编号系统
UNII：36B82AMQ7N
物化性质
外观与性状：白色至略灰白色粉末
密度：1.43 g/cm3
沸点：532.8ºC at 760 mmHg
熔点：184ºC
闪点：276.1ºC
稳定性：Not particularly hygroscopic; can oxidize; relatively stable in heat hydrochloride.
储存条件：Protect from excessive light.Should be protected from excessive moisture and exposure to air.Should be stored below 30ºC.
密度：1.43 g/cm3
沸点：532.8ºC at 760 mmHg
熔点：184ºC
闪点：276.1ºC
稳定性：Not particularly hygroscopic; can oxidize; relatively stable in heat hydrochloride.
储存条件：Protect from excessive light.Should be protected from excessive moisture and exposure to air.Should be stored below 30ºC.
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
