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  • 左醋美沙朵乙酸酯盐酸盐

    (-)-α-Acetylmethadol Hydrochloride

化合物简介

Levacetylmethadol (INN), levomethadyl acetate (USAN), OrLAAM (trade name) or levo-α-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone. It has a long duration of action due to its active metabolites. It was approved in 1993 by the U.S. Food and Drug Administration for use in the treatment of opioid dependence. In 2001, levacetylmethadol was removed from the European market due to reports of life-threatening ventricular rhythm disorders. In 2003, Roxane Laboratories, Inc. discontinued Orlaam in the US.

基本信息

CAS:43033-72-3
中文别名
英文别名:Levomethadyl acetate hydrochloride;
分子式:C23H32ClNO2
分子量:389.959
精确质量:389.212
Psa:29.54
Logp:5.4566

编号系统

UNII:B54CW5KG52

物化性质

沸点:456ºC at 760 mmHg
闪点:130ºC
储存条件:库房通风低温干燥

安全信息

海关编码:2922199090

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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