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化合物简介
Estradiol acetate (INN, USAN, BAN; brand names Femtrace, Femring, Menoring) is a synthetic ester, specifically the 3-O-acetyl ester, of the natural estrogen, estradiol. It is relatively recent to the market, having been first approved in a vaginal ring formulation as Menoring in the United Kingdom in 2001, followed by another vaginal ring formulation as Femring in the United States in 2003, and finally as an oral preparation as Femtrace in the United States in 2004. It is used as a form of hormone replacement therapy to treat and prevent symptoms of menopause such as osteoporosis in postmenopausal women.
基本信息
CAS:4245-41-4
中文别名:
英文别名:3-O-acetyl-β-estradiol;[(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] acetate;3,17β-estradiol 3-acetate;3-acetylestradiol;estradiol 3-acetate;3-acetoxy-estratrien-(1.3.5(10))-ol-(17β);(8R)-17c-Hydroxy-3-acetoxy-13c-methyl-(8rH.9tH.14tH)-7.8.9.11.12.13.14.15.16.17-decahydro-6H-cyclopenta[a]phenanthren;
分子式:C20H26O3
分子量:314.419
精确质量:314.188
Psa:46.53
Logp:3.8289
中文别名:
英文别名:3-O-acetyl-β-estradiol;[(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] acetate;3,17β-estradiol 3-acetate;3-acetylestradiol;estradiol 3-acetate;3-acetoxy-estratrien-(1.3.5(10))-ol-(17β);(8R)-17c-Hydroxy-3-acetoxy-13c-methyl-(8rH.9tH.14tH)-7.8.9.11.12.13.14.15.16.17-decahydro-6H-cyclopenta[a]phenanthren;
分子式:C20H26O3
分子量:314.419
精确质量:314.188
Psa:46.53
Logp:3.8289
编号系统
UNII:5R97F5H93P
物化性质
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict


