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  • 托利咪酮

    5-(3-methylphenoxy)-1H-pyrimidin-2-one

化合物简介

Tolimidone (MLR-1023) is an allosteric Lyn kinase activator that has been shown to reduce blood glucose levels in mice. Studies show that Tolimidone is an effective insulin receptor-potentiating agent that is potentially capable of producing durable blood glucose-lowering activity in diabetics. Tolimidone is a candidate for the treatment of type 2 diabetes.

基本信息

CAS:41964-07-2
中文别名:5-(3-甲基苯酚基)-2-(1H)-嘧啶酮;
英文别名:QCR-285;Tolimidone (USAN);UNII-MU3JD8E9IS;5-(3-Methylphenoxy)- 2(1H)-pyrimidinone CP 26154;TOLIMIDONE;5-(m-Tolyloxy)-2-(1H)-pyrimidinon;Tolimidone [USAN:INN];5-m-tolyloxy-1H-pyrimidin-2-one;5-(3-methylphenoxy)-2(1H)-pyrimidinone;
分子式:C11H10N2O2
分子量:202.209
精确质量:202.074
Psa:54.98
Logp:1.8706

编号系统

UNII:MU3JD8E9IS

物化性质

密度:1.22g/cm3
熔点:163-164ºC
折射率:1.598

安全信息

海关编码:2933599090
危险性描述:H319
信号词:Warning
危险标志:GHS07
危险性防范说明:P305 + P351 + P338

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


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