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化合物简介
Nerolidol, also known as peruviol, is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. There are two isomers of nerolidol, cis and trans, which differ in the geometry about the central double bond. Nerolidol is present in neroli, ginger, jasmine, lavender, tea tree, Cannabis sativa, and lemon grass, and is a dominant scent compound in Brassavola nodosa. The aroma of nerolidol is woody and reminiscent of fresh bark. It is used as a flavoring agent and in perfumery. It is also currently under testing as a skin penetration enhancer for the transdermal delivery of therapeutic drugs.
基本信息
CAS:40716-66-3
中文别名:
英文别名:trans-N-Cyclohexyl-2,3-dibenzoyl-aziridin;trans-1-Cyclohexyl-2,3-dibenzoyl-aziridin;3,7,11-trimethyldodeca-1,6,10-trien-3-ol;(E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol,trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol;
分子式:C15H26O
分子量:222.366
精确质量:222.198
Psa:20.23
Logp:4.3963
中文别名:
英文别名:trans-N-Cyclohexyl-2,3-dibenzoyl-aziridin;trans-1-Cyclohexyl-2,3-dibenzoyl-aziridin;3,7,11-trimethyldodeca-1,6,10-trien-3-ol;(E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol,trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol;
分子式:C15H26O
分子量:222.366
精确质量:222.198
Psa:20.23
Logp:4.3963
编号系统
EINECS号:255-053-4
物化性质
密度:0.875
沸点:114ºC (1 mmHg)
闪点:96ºC
折射率:1.479
沸点:114ºC (1 mmHg)
闪点:96ºC
折射率:1.479
安全信息
安全说明:S26-S36
危险类别码:R36/37/38
海关编码:2905290000
危险品标志:Xi
危险性描述:H315; H319; H335
信号词:Warning
危险标志:GHS07
危险性防范说明:P261; P305 + P351 + P338
危险类别码:R36/37/38
海关编码:2905290000
危险品标志:Xi
危险性描述:H315; H319; H335
信号词:Warning
危险标志:GHS07
危险性防范说明:P261; P305 + P351 + P338
生产方法及用途
生产方法
1. 烟草:FC,18;采用芳樟醇为原料,先将芳樟醇转化为香叶基丙酮,炔化后成为脱氢橙花叔醇,经加氢后即成为橙花叔醇。
1. 烟草:FC,18;采用芳樟醇为原料,先将芳樟醇转化为香叶基丙酮,炔化后成为脱氢橙花叔醇,经加氢后即成为橙花叔醇。
合成路线
-
参考文献
Fourneron, Jean-Dominique; Julia, Marc Bulletin de la Societe Chimique de France, 1981 , vol. 2, # 9-10 p. 387 - 392
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict













