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化合物简介
1-(4-Chlorophenyl)biguanide is a guanide derivative that can inhibit significantly dihydrofolate reductase (DHFR).
基本信息
CAS：4022-81-5
中文别名：1-(4-氯苯基)双胍盐酸盐;
英文别名：amp;1-(4-Chlorophenyl)biguanideHCl;N1-(p-Chlorophenyl)biguanide hydrochloride;1-(4-Chlor-phenyl)-biguanid,Hydrochlorid;1-(p-chlorophenyl)biguanidehydrochloride;1-(p-Chlorophenyl)biguanide Monohydroch;1-(p-Chlorophenyl)biguanide Monohydrochloride;1-(p-chlorophenyl)-biguanidmonohydrochloride;N-(4-chlorophenyl)imidodicarbonimidic diamide hydrochloride;imidodicarbonimidic diamide,N-(4-chlorophenyl);1-(4-CHLOROPHENYL)BIGUANIDE HYDROCHLOR&BUTTPARK 451-24;N1-4\'-chlorophenyl-biguanide hydrochloride;1-(4-chloro-phenyl)-biguanide,hydrochloride;
分子式：C8H11Cl2N5
分子量：248.112
精确质量：247.039
Psa：97.78
Logp：3.3354
中文别名：1-(4-氯苯基)双胍盐酸盐;
英文别名：amp;1-(4-Chlorophenyl)biguanideHCl;N1-(p-Chlorophenyl)biguanide hydrochloride;1-(4-Chlor-phenyl)-biguanid,Hydrochlorid;1-(p-chlorophenyl)biguanidehydrochloride;1-(p-Chlorophenyl)biguanide Monohydroch;1-(p-Chlorophenyl)biguanide Monohydrochloride;1-(p-chlorophenyl)-biguanidmonohydrochloride;N-(4-chlorophenyl)imidodicarbonimidic diamide hydrochloride;imidodicarbonimidic diamide,N-(4-chlorophenyl);1-(4-CHLOROPHENYL)BIGUANIDE HYDROCHLOR&BUTTPARK 451-24;N1-4\'-chlorophenyl-biguanide hydrochloride;1-(4-chloro-phenyl)-biguanide,hydrochloride;
分子式：C8H11Cl2N5
分子量：248.112
精确质量：247.039
Psa：97.78
Logp：3.3354
编号系统
MDL号：MFCD00053020
BRN号：3732533
PubChem号：24874789
RTECS号：DU1780200
BRN号：3732533
PubChem号：24874789
RTECS号：DU1780200
物化性质
沸点：426.4ºC at 760 mmHg
熔点：239-242°C(lit.)
闪点：211.7ºC
蒸汽压：1.78E-07mmHg at 25°C
熔点：239-242°C(lit.)
闪点：211.7ºC
蒸汽压：1.78E-07mmHg at 25°C
安全信息
RTECS号：DU1780200
安全说明：S26-S36
危险类别码：R36/37/38
WGK Germany：3
危险品标志：Xi
安全说明：S26-S36
危险类别码：R36/37/38
WGK Germany：3
危险品标志：Xi
生产方法及用途
合成路线
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参考文献
Chen, Huixiong; Dao, Pascal; Laporte, Alice; Garbay, Christiane Tetrahedron Letters, 2010 , vol. 51, # 24 p. 3174 - 3176
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
