Triptolide, sold under the brandname Minnelide is a diterpenoid epoxide found in the Thunder God Vine, Tripterygium wilfordii. It has in vitro and in vivo activities against mouse models of polycystic kidney disease and pancreatic cancer, but its physical properties limit its therapeutic potential. Consequently, a synthetic prodrug, minnelide, is being studied clinically instead.

CAS：38748-32-2
中文别名：雷藤素甲;雷公藤内酯醇;
英文别名：(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one;TRIPTOLIDE;Triptolide (PG490);triptolid;PG490;,7as,7bs,8as,8bs);triptergium wilfordii;(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-6a-isopropyl-8b-methyltrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one;Triptolide?;TRIPTOLIDE TLC;Triptolide(PG490);
分子式：C20H24O6
分子量：360.401
精确质量：360.157
Psa：84.12
Logp：1.1031

UNII：19ALD1S53J

外观与性状：白色至灰白色固体
密度：1.48 g/cm3
沸点：601.7ºC at 760 mmHg
熔点：226-227°C
闪点：220.7ºC
折射率：1.647
储存条件：2-8ºC

RTECS号：YK7751000
安全说明：S22; S24/25
WGK Germany：3