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3-azido-5-{6-[5-chloro-2-(3-methylisoxazol-5-ylmethoxy) benzylamino]purin-9-yl}-4-hydroxytetrahydrofuran-2-carboxylic acid methylamide
化合物简介
基本信息
CAS：331728-88-2
中文别名：
英文别名：(2S,3S,4R,5R)-3-Azido-5-{6-[5-chloro-2-(3-methyl-isoxazol-5-ylmethoxy)-benzylamino]-purin-9-yl}-4-hydroxy-tetrahydro-furan-2-carboxylic acid methylamide;(2S,3S,4R,5R)3-azido-5-{6-[5-chloro-2-(3-methylisoxazol-5-ylmethoxy)benzylamino]purin-9-yl}4-hydroxytetrahydrofuran-2-carboxylic acid methylamide;
分子式：C23H23ClN10O5
分子量：554.946
精确质量：554.154
Psa：199.2
Logp：2.56706
中文别名：
英文别名：(2S,3S,4R,5R)-3-Azido-5-{6-[5-chloro-2-(3-methyl-isoxazol-5-ylmethoxy)-benzylamino]-purin-9-yl}-4-hydroxy-tetrahydro-furan-2-carboxylic acid methylamide;(2S,3S,4R,5R)3-azido-5-{6-[5-chloro-2-(3-methylisoxazol-5-ylmethoxy)benzylamino]purin-9-yl}4-hydroxytetrahydrofuran-2-carboxylic acid methylamide;
分子式：C23H23ClN10O5
分子量：554.946
精确质量：554.154
Psa：199.2
Logp：2.56706
编号系统
物化性质
熔点：94 - 98 °C
安全信息
生产方法及用途
合成路线
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参考文献
DeNinno, Michael P.; Masamune, Hiroko; Chenard, Lois K.; DiRico, Kenneth J.; Eller, Cynthia; Etienne, John B.; Tickner, Jeanene E.; Kennedy, Scott P.; Knight, Delvin R.; Kong, Jimmy; Oleynek, Joseph J.; Tracey, W. Ross; Hill, Roger J. Journal of Medicinal Chemistry, 2003, vol. 46, # 3 p. 353 - 355 doi: 10.1021/jm0255724
