Bombesin is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina). It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide. It stimulates gastrin release from G cells. It activates three different G-protein-coupled receptors known as BBR1, -2, and -3. It also activates these receptors in the brain. Together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour.

CAS：31362-50-2
中文别名：铃蟾肽;
英文别名：Alphaxalone;bombesin acetate hydrate;BOMBESIN ACOH 7H2O;BOMBESIN ACETATE SALT;M.W. 1619.85 C71H110N24O18S;PYR-QRLGNQWAVGHLM-NH2;pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2;bombesin acetate;
分子式：C71H110N24O18S
分子量：1619.85
精确质量：1618.82
Psa：711.43
Logp：2.5988

UNII：PX9AZU7QPK

外观与性状：冻干的粉末
密度：1.5g/cm3
折射率：1.681
储存条件：-20ºC

安全说明：S22; S24/25

用途
诊断药物。神经节母细胞瘤和甲状腺髓质癌患者血中BBS免疫反应物浓度升高;可作为判断胃窦是否完全切除的试验剂。