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  • 环戊丙酸雌二醇

    β-Estradiol 17-cypionate

化合物简介

Estradiol cypionate (INN, USAN) (brand names Depo-Estradiol, Depofemin, Estradep, and many others), or estradiol cipionate, also known as estradiol 3-cyclopentylpropionate, is a synthetic estrogen ester, specifically the 3-cyclopentylpropanoyl ester, of the natural estrogen estradiol. It was first introduced in 1952 by Upjohn in the United States, and has been in widespread use since. Estradiol cypionate behaves as a sustained-release prodrug to estradiol, and therefore is considered to be natural estrogen.

基本信息

CAS:313-06-4
中文别名:Β-雌二醇-17-脓蓝素;β-雌二醇-17-环戊丙酸酯;
英文别名:Depofemin;β-Estradiol 17-Cyclopentylpropionate;Estradiol Cypionate;
分子式:C26H36O3
分子量:396.562
精确质量:396.266
Psa:46.53
Logp:6.1305

编号系统

UNII:7E1DV054LO

物化性质

外观与性状:白色或灰白色结晶粉末
密度:1.15g/cm3
沸点:532.8ºC at 760mmHg
熔点:≥300°C(lit.)
闪点:207.7ºC
折射率:1.579

安全信息

RTECS号:KG4600000
安全说明:S53-S22-S36/37/39-S45-S26
危险类别码:R20/21/22; R36/37/38; R45; R46; R61
WGK Germany:3
危险品标志:T

生产方法及用途

用途
长效雌激素。

合成路线

上游原料

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


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