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化合物简介
Estradiol cypionate (INN, USAN) (brand names Depo-Estradiol, Depofemin, Estradep, and many others), or estradiol cipionate, also known as estradiol 3-cyclopentylpropionate, is a synthetic estrogen ester, specifically the 3-cyclopentylpropanoyl ester, of the natural estrogen estradiol. It was first introduced in 1952 by Upjohn in the United States, and has been in widespread use since. Estradiol cypionate behaves as a sustained-release prodrug to estradiol, and therefore is considered to be natural estrogen.
基本信息
CAS:313-06-4
中文别名:Β-雌二醇-17-脓蓝素;β-雌二醇-17-环戊丙酸酯;
英文别名:Depofemin;β-Estradiol 17-Cyclopentylpropionate;Estradiol Cypionate;
分子式:C26H36O3
分子量:396.562
精确质量:396.266
Psa:46.53
Logp:6.1305
中文别名:Β-雌二醇-17-脓蓝素;β-雌二醇-17-环戊丙酸酯;
英文别名:Depofemin;β-Estradiol 17-Cyclopentylpropionate;Estradiol Cypionate;
分子式:C26H36O3
分子量:396.562
精确质量:396.266
Psa:46.53
Logp:6.1305
编号系统
UNII:7E1DV054LO
物化性质
外观与性状:白色或灰白色结晶粉末
密度:1.15g/cm3
沸点:532.8ºC at 760mmHg
熔点:≥300°C(lit.)
闪点:207.7ºC
折射率:1.579
密度:1.15g/cm3
沸点:532.8ºC at 760mmHg
熔点:≥300°C(lit.)
闪点:207.7ºC
折射率:1.579
安全信息
RTECS号:KG4600000
安全说明:S53-S22-S36/37/39-S45-S26
危险类别码:R20/21/22; R36/37/38; R45; R46; R61
WGK Germany:3
危险品标志:T
安全说明:S53-S22-S36/37/39-S45-S26
危险类别码:R20/21/22; R36/37/38; R45; R46; R61
WGK Germany:3
危险品标志:T
生产方法及用途
用途
长效雌激素。
长效雌激素。
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict

Mass spectrum (electron ionization)
