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化合物简介
Hycanthone is the schistosomicide approved by the FDA in 1975. It is a metabolite of lucanthone. Hycanthone interferes with parasite nerve function, resulting in paralysis and death. This agent also intercalates into DNA and inhibits RNA synthesis in vitro and shows potential antineoplastic activity.
基本信息
CAS:3105-97-3
中文别名:1-[(2-[二乙基氨基]乙基)氨基]-4-[羟基甲基]-9h-噻吨酮;
英文别名:lucanthonemetabolite;1-(2-diethylaminoethylamino)-4-methylol-thioxanthen-9-one;1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE;1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one;ETRENOL;hycanthon;Etrenol(mesylate);1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-9h-thioxanthen-9-on;HYCANTHONE;Win 249-33;
分子式:C20H24N2O2S
分子量:356.482
精确质量:356.156
Psa:80.81
Logp:3.7337
中文别名:1-[(2-[二乙基氨基]乙基)氨基]-4-[羟基甲基]-9h-噻吨酮;
英文别名:lucanthonemetabolite;1-(2-diethylaminoethylamino)-4-methylol-thioxanthen-9-one;1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE;1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one;ETRENOL;hycanthon;Etrenol(mesylate);1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-9h-thioxanthen-9-on;HYCANTHONE;Win 249-33;
分子式:C20H24N2O2S
分子量:356.482
精确质量:356.156
Psa:80.81
Logp:3.7337
编号系统
MDL号:MFCD00083383
物化性质
密度:1.25g/cm3
沸点:570.5ºC at 760mmHg
熔点:approx 143ºC
闪点:298.9ºC
折射率:1.658
储存条件:-20ºC
沸点:570.5ºC at 760mmHg
熔点:approx 143ºC
闪点:298.9ºC
折射率:1.658
储存条件:-20ºC
安全信息
危险类别码:R45; R46; R20/21/22
海关编码:2932999099
危险品标志:T
海关编码:2932999099
危险品标志:T
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict



