Geldanamycin is a 1,4-benzoquinone ansamycin antitumor antibiotic that inhibits the function of Hsp90 (Heat Shock Protein 90) by binding to the unusual ADP/ATP-binding pocket of the protein. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis.

CAS：30562-34-6
中文别名：粉防己碱;
英文别名：GeldanaMycin;Geldanamycin from Streptomyces hygroscopicus;GELDANAMYCIN,STREPTOMYCES HYGROSCOPICUS;GELDANAMYCIN FROM STRE;Streptomyces hygroscopicus;
分子式：C29H40N2O9
分子量：560.636
精确质量：560.273
Psa：163.48
Logp：3.4375

MDL号：MFCD00274570

外观与性状：黄色至橙色粉末
密度：1.23 g/cm3
沸点：783.9ºC at 760 mmHg
熔点：255 °C
闪点：427.9ºC
折射率：1.559
储存条件：-20ºC

RTECS号：LX8920000
安全说明：S26; S27; S36/37/39
WGK Germany：2
危险类别码：R36/37/38
海关编码：2933990090
危险品标志：T

用途
生化研究