Methylestradiol, or 17α-methylestradiol (17α-ME), is a semisynthetic, steroidal estrogen that has been sold in combination with normethandrone (methylestrenolone), a progestin and weak androgen/anabolic steroid, under brand names including Ginecosid, Ginecoside, Mediol, Renodiol for the treatment of menopausal symptoms in Brazil, Venezuela, and Indonesia. Due to the presence of the 17α-methyl group, methylestradiol cannot be deactivated by oxidation of the 17β-hydroxy group, resulting in improved metabolic stability and potency relative to estradiol analogously to ethinyl estradiol (17α-ethinylestradiol). In addition to its clinical use, methylestradiol has been studied as a radiopharmaceutical.

CAS：302-76-1
中文别名：
英文别名：17alpha-Methylestradiol;Methylestradiol;17-Methylestradiol;
分子式：C19H26O2
分子量：286.409
精确质量：286.193
Psa：40.46
Logp：3.9993

UNII：08IS5358PS

密度：1.14g/cm3
沸点：444.8ºC at 760mmHg
闪点：205.7ºC
折射率：1.584