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化合物简介

Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase.

基本信息

CAS:298-45-3
中文别名:球紫堇碱;
英文别名:Bulbocapnine;10-Methoxy-6-methyl-1,2-methylendioxy-aporphan-11-ol;5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-12-ol, 6,7,7a,8-tetrahydro-11-methoxy-7-methyl-, (S)-;4-Hydroxy-3-methoxy-5,6-methylenedioxy-aporphin;Bulbokaprin;
分子式:C19H19NO4
分子量:325.358
精确质量:325.131
Psa:51.16
Logp:2.8195

编号系统

EINECS号:206-061-1

物化性质

密度:1.342g/cm3
沸点:504ºC at 760mmHg
熔点:199-200ºC
闪点:258.6ºC
折射率:1.653
蒸汽压:8.84E-11mmHg at 25°C

安全信息

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


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