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2-[3,5-二(三氟甲基)苯基]-N,2-二甲基-N-[4-(2-甲基苯基)-6-吗啉-4-基-吡啶-3-基]丙酰胺
2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-morpholin-4-ylpyridin-3-yl]propanamide
化合物简介
Befetupitant (Ro67-5930) is a drug developed by Hoffmann-La Roche which acts as a potent and selective antagonist for the NK1 receptor. It was originally developed as a potential antiemetic drug, though development was ultimately discontinued after a related drug netupitant was deemed to be more suitable for clinical development. Befetupitant has however continued to be researched for other possible applications such as treatment of corneal neovascularization.
基本信息
CAS：290296-68-3
中文别名：
英文别名：Befetupitant;UNII-RSH7NDI7MI;Ro 67-5930;
分子式：C29H29F6N3O2
分子量：565.55
精确质量：565.216
Psa：45.67
Logp：6.9368
中文别名：
英文别名：Befetupitant;UNII-RSH7NDI7MI;Ro 67-5930;
分子式：C29H29F6N3O2
分子量：565.55
精确质量：565.216
Psa：45.67
Logp：6.9368
编号系统
UNII：RSH7NDI7MI
物化性质
密度：1.283g/cm3
沸点：599.8ºC at 760mmHg
闪点：316.6ºC
折射率：1.537
蒸汽压：2.39E-14mmHg at 25°C
沸点：599.8ºC at 760mmHg
闪点：316.6ºC
折射率：1.537
蒸汽压：2.39E-14mmHg at 25°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
