tert-butyl 4-[N-[7-chloro-3-methyl-2-(methyl-L-prolin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate tert-butyl 4-[N-[7-chloro-3-methyl-2-(methyl-L-prolin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate CAS号289686-96-0分子式、结构式、MSDS、物化性质、用途-化学科研者一站式服务平台

化合物简介

基本信息

CAS：289686-96-0
中文别名：
英文别名：(S)-1-(6-{[(4-tert-Butoxycarbonyl-phenyl)-prop-2-ynyl-amino]-methyl}-7-chloro-3-methyl-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl)-pyrrolidine-2-carboxylic acid methyl ester;tert-butyl 4-[N-[7-chloro-3-methyl-2-(methyl-L-prolin-1-yl)methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate;
分子式：C31H35ClN4O5
分子量：579.086
精确质量：578.23
Psa：93.97
Logp：4.2573

编号系统

物化性质

熔点：69 - 70 °C

安全信息

生产方法及用途

合成路线

参考文献

Bavetsias; Skelton; Yafai; Mitchell; Wilson; Allan; Jackman Journal of Medicinal Chemistry, 2002, vol. 45, # 17 p. 3692 - 3702 doi: 10.1021/jm011081s

上游原料

458533-73-8
2-methoxyacetamido-4-chloro-5-methyl N-methylbenzamide

化学科研者一站式服务平台

tert-butyl 4-[N-[7-chloro-3-methyl-2-(methyl-L-prolin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate