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  • Scriptaid

    6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide

化合物简介

Scriptaid is a drug which acts as a histone deacetylase inhibitor, and was one of the first compounds discovered via high-throughput screening that acts at this target. Scriptaid itself was never developed for medical applications, but led to the development of structurally related drugs such as vorinostat which have been accepted into clinical use. Most early research using these compounds focused on their anti-cancer activity, but more recent research has found scriptaid to be useful in other applications such as cloning and research into regulation of metabolism.

基本信息

CAS:287383-59-9
中文别名
英文别名:GNF-PF-2024;CGK1026;Scriptide,GCK 1026;1H-Benz[de]isoquinoline-2(3H)-hexanamide,N-hydroxy-1,3-dioxo;Scriptide;scriptaid;
分子式:C18H18N2O4
分子量:326.347
精确质量:326.127
Psa:88.4
Logp:2.4094

编号系统

物化性质

密度:1.338g/cm3
折射率:1.646
储存条件:-20ºC

安全信息

海关编码:2933990090

生产方法及用途

合成路线

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图谱

Predict 1H proton NMR


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