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化合物简介
Scriptaid is a drug which acts as a histone deacetylase inhibitor, and was one of the first compounds discovered via high-throughput screening that acts at this target. Scriptaid itself was never developed for medical applications, but led to the development of structurally related drugs such as vorinostat which have been accepted into clinical use. Most early research using these compounds focused on their anti-cancer activity, but more recent research has found scriptaid to be useful in other applications such as cloning and research into regulation of metabolism.
基本信息
CAS:287383-59-9
中文别名:
英文别名:GNF-PF-2024;CGK1026;Scriptide,GCK 1026;1H-Benz[de]isoquinoline-2(3H)-hexanamide,N-hydroxy-1,3-dioxo;Scriptide;scriptaid;
分子式:C18H18N2O4
分子量:326.347
精确质量:326.127
Psa:88.4
Logp:2.4094
中文别名:
英文别名:GNF-PF-2024;CGK1026;Scriptide,GCK 1026;1H-Benz[de]isoquinoline-2(3H)-hexanamide,N-hydroxy-1,3-dioxo;Scriptide;scriptaid;
分子式:C18H18N2O4
分子量:326.347
精确质量:326.127
Psa:88.4
Logp:2.4094
编号系统
物化性质
密度:1.338g/cm3
折射率:1.646
储存条件:-20ºC
折射率:1.646
储存条件:-20ºC
安全信息
海关编码:2933990090
生产方法及用途
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR
