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  • 尼日利亚菌素

    nigericin

化合物简介

Nigericin is an antibiotic derived from Streptomyces hygroscopicus. Its isolation was described in the 1950s, and in 1968 the structure could be elucidated by X-ray crystallography. The structure and properties of nigericin are similar to the antibiotic monensin. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of Geldanamycin. It is also called Polyetherin A, Azalomycin M, Helixin C, Antibiotic K178, Antibiotic X-464.

基本信息

CAS:28380-24-7
中文别名
英文别名:Nigericin;AZALOMYCIN M;POLYETHERIN A;Helix c;NIGERICIN NA;x-464;HELIXIN C;ANTIBIOTIC K178;
分子式:C40H67NaO11
分子量:746.943
精确质量:746.458
Psa:145.2
Logp:4.3709

编号系统

UNII:RRU6GY95IS

物化性质

外观与性状:白色固体
密度:1.19g/cm3
沸点:779.9ºC at 760mmHg
熔点:245-255ºC
闪点:226.9ºC
折射率:1.543
储存条件:2-8ºC

安全信息

危险品运输编码:UN 3462 6
危险类别:6.1(b)
包装等级:III
危险品标志:T

生产方法及用途

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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