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化合物简介
1-Bis(4-fluorophenyl)methyl Piperzaine is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives.
基本信息
CAS:27469-60-9
中文别名:1-(4,4\'-二氟苯甲基)哌嗪;1-(4,4\'-二氟二苯甲基)哌嗪;二(对氟苯基)甲基哌嗪;对二氟苯甲基哌嗪(洛美利嗪中间体IV;1-(双(对氟苯基)甲基)哌嗪;双(4-氟苯基)甲基哌嗪;1-双(4-氟苯基)甲基哌嗪;1-[双(4-氟苯基)甲基]哌嗪;哌嗪基双(4-氟苯)甲烷;
英文别名:1-[Bis-(4-fluorophenyl)methyl]piperazine;1-(4,4\'-Difluorodiphenylmethyl)piperazine;1-(4,4\'-Difluorobenzhydryl)piperazine;1-(Bis(4-fluorophenyl)methyl)piperazine;1-Bis(4-fluorophenyl)methyl piperazine;4,4\'-Difluorobenzhydrylpiperazine;N-[bis(4-fluorophenyl)methyl]piperazine;1-[(4\',4\'\'-difluorodiphenyl)methyl]piperazine;1-(4,4\'-difluorobenzhydryl)piperazine;[bis(4-fluorophenyl)methyl]piperazine;1-[Bis(4-fluorophenyl)methyl]piperazine;1-[bis-(p-fluorophenyl)methyl]piperazine;
分子式:C17H18F2N2
分子量:288.335
精确质量:288.144
Psa:15.27
Logp:3.2261
中文别名:1-(4,4\'-二氟苯甲基)哌嗪;1-(4,4\'-二氟二苯甲基)哌嗪;二(对氟苯基)甲基哌嗪;对二氟苯甲基哌嗪(洛美利嗪中间体IV;1-(双(对氟苯基)甲基)哌嗪;双(4-氟苯基)甲基哌嗪;1-双(4-氟苯基)甲基哌嗪;1-[双(4-氟苯基)甲基]哌嗪;哌嗪基双(4-氟苯)甲烷;
英文别名:1-[Bis-(4-fluorophenyl)methyl]piperazine;1-(4,4\'-Difluorodiphenylmethyl)piperazine;1-(4,4\'-Difluorobenzhydryl)piperazine;1-(Bis(4-fluorophenyl)methyl)piperazine;1-Bis(4-fluorophenyl)methyl piperazine;4,4\'-Difluorobenzhydrylpiperazine;N-[bis(4-fluorophenyl)methyl]piperazine;1-[(4\',4\'\'-difluorodiphenyl)methyl]piperazine;1-(4,4\'-difluorobenzhydryl)piperazine;[bis(4-fluorophenyl)methyl]piperazine;1-[Bis(4-fluorophenyl)methyl]piperazine;1-[bis-(p-fluorophenyl)methyl]piperazine;
分子式:C17H18F2N2
分子量:288.335
精确质量:288.144
Psa:15.27
Logp:3.2261
编号系统
MDL号:MFCD00038660
物化性质
外观与性状:白色至灰白色粉末
密度:1.181 g/cm3
沸点:130 °C
熔点:88-92°C(lit.)
水溶解性:0.34 g/L (20 ºC)
稳定性:Stable under normal temperatures and pressures.
储存条件:Store in a cool, dry place. Store in a tightly closed container.
蒸汽压:1.32E-05mmHg at 25°C
密度:1.181 g/cm3
沸点:130 °C
熔点:88-92°C(lit.)
水溶解性:0.34 g/L (20 ºC)
稳定性:Stable under normal temperatures and pressures.
储存条件:Store in a cool, dry place. Store in a tightly closed container.
蒸汽压:1.32E-05mmHg at 25°C
安全信息
安全说明:S26-S45-S36/37/39
危险类别码:R25; R36/37/38
WGK Germany:3
危险品运输编码:UN 2811 6.1/PG 3
包装等级:I; II; III
危险品标志:T
危险类别码:R25; R36/37/38
WGK Germany:3
危险品运输编码:UN 2811 6.1/PG 3
包装等级:I; II; III
危险品标志:T
生产方法及用途
用途
用作医药氟桂嗪中间体
用作医药氟桂嗪中间体
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict
