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  • 异硫氰酸荧光素

    Fluorescein isothiocyanate

化合物简介

Fluorescein isothiocyanate (FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. FITC is the original fluorescein molecule functionalized with an isothiocyanate reactive group (-N=C=S), replacing a hydrogen atom on the bottom ring of the structure. This derivative is reactive towards nucleophiles including amine and sulfhydryl groups on proteins.

基本信息

CAS:27072-45-3
中文别名:异硫氰酸荧光素(5-,6-异构体混合物);异硫氰荧光素;异硫氰酸荧光素(FITC);荧光素5(6)-异硫氰酸酯;
英文别名:FITC-I;Fluorescein Isothiosyanate;Isothiocyanatofluorescein;5-FITC;5-Isothionatofluorescein;Fluorescein Isothiocyanate;FITC ISOMER;Fluorescein 5(6)-isothiocyanate;FITC isomer I;FITC;Fluorescein-5-isothiocyanate;fluorescein isothiocyanate isomer 1;
分子式:C21H11NO5S
分子量:389.381
精确质量:389.036
Psa:120.44
Logp:4.4001

编号系统

UNII:7BUU93N0HM

物化性质

密度:1.54g/cm3
沸点:708.6ºC at 760mmHg
熔点:>360ºC(lit.)
闪点:382.4ºC
折射率:1.753
储存条件:2-8ºC
蒸汽压:9.53E-21mmHg at 25°C

安全信息

安全说明:S22
危险类别码:R42/43
WGK Germany:3
危险品标志:Xn
危险性描述:H334
危险性防范说明:P261; P342 + P311
危险标志:GHS08
信号词:Danger

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


Mass


IR : KBr disc


IR : nujol mull


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