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化合物简介
Fluorescein isothiocyanate (FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. FITC is the original fluorescein molecule functionalized with an isothiocyanate reactive group (-N=C=S), replacing a hydrogen atom on the bottom ring of the structure. This derivative is reactive towards nucleophiles including amine and sulfhydryl groups on proteins.
基本信息
CAS:27072-45-3
中文别名:异硫氰酸荧光素(5-,6-异构体混合物);异硫氰荧光素;异硫氰酸荧光素(FITC);荧光素5(6)-异硫氰酸酯;
英文别名:FITC-I;Fluorescein Isothiosyanate;Isothiocyanatofluorescein;5-FITC;5-Isothionatofluorescein;Fluorescein Isothiocyanate;FITC ISOMER;Fluorescein 5(6)-isothiocyanate;FITC isomer I;FITC;Fluorescein-5-isothiocyanate;fluorescein isothiocyanate isomer 1;
分子式:C21H11NO5S
分子量:389.381
精确质量:389.036
Psa:120.44
Logp:4.4001
中文别名:异硫氰酸荧光素(5-,6-异构体混合物);异硫氰荧光素;异硫氰酸荧光素(FITC);荧光素5(6)-异硫氰酸酯;
英文别名:FITC-I;Fluorescein Isothiosyanate;Isothiocyanatofluorescein;5-FITC;5-Isothionatofluorescein;Fluorescein Isothiocyanate;FITC ISOMER;Fluorescein 5(6)-isothiocyanate;FITC isomer I;FITC;Fluorescein-5-isothiocyanate;fluorescein isothiocyanate isomer 1;
分子式:C21H11NO5S
分子量:389.381
精确质量:389.036
Psa:120.44
Logp:4.4001
编号系统
UNII:7BUU93N0HM
物化性质
密度:1.54g/cm3
沸点:708.6ºC at 760mmHg
熔点:>360ºC(lit.)
闪点:382.4ºC
折射率:1.753
储存条件:2-8ºC
蒸汽压:9.53E-21mmHg at 25°C
沸点:708.6ºC at 760mmHg
熔点:>360ºC(lit.)
闪点:382.4ºC
折射率:1.753
储存条件:2-8ºC
蒸汽压:9.53E-21mmHg at 25°C
安全信息
安全说明:S22
危险类别码:R42/43
WGK Germany:3
危险品标志:Xn
危险性描述:H334
危险性防范说明:P261; P342 + P311
危险标志:GHS08
信号词:Danger
危险类别码:R42/43
WGK Germany:3
危险品标志:Xn
危险性描述:H334
危险性防范说明:P261; P342 + P311
危险标志:GHS08
信号词:Danger
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict

Mass

IR : KBr disc

IR : nujol mull
