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化合物简介

Zotepine (brand names: Losizopilon (JP), Lodopin (ID, JP), Setous (JP), Zoleptil (CZ, PT, TR, UK†); where † indicates a formulation that has been discontinued) is an atypical antipsychotic drug indicated for acute and chronic schizophrenia. It has been used in Germany since 1990 (although it has been discontinued in Germany) and Japan since 1982.

基本信息

CAS:26615-21-4
中文别名:泽坦平;2-[(8-氯二苯并[b,f]硫杂卓-10-基)氧基]-N,N-二甲基乙胺;
英文别名:2-(3-chlorobenzo[b][1]benzothiepin-5-yl)oxy-N,N-dimethylethanamine;Setous;Compound-4;Zotepinum;Nipolept;Zotepina;Lodopin;
分子式:C18H18ClNOS
分子量:331.86
精确质量:331.08
Psa:37.77
Logp:4.8809

编号系统

UNII:U29O83JAZW

物化性质

密度:1.27 g/cm3
沸点:478.4ºC at 760 mmHg
闪点:243.2ºC
折射率:1.655
蒸汽压:2.57E-09mmHg at 25°C

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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