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化合物简介
Dapivirine (TMC120) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed at Janssen Therapeutics (formerly Tibotec Therapeutics). The International Partnership for Microbicides (IPM) has held exclusive worldwide rights to dapivirine since 2014, building upon a 2004 royalty-free license to develop dapivirine-based microbicides for women in resource-poor countries.
基本信息
CAS：244767-67-7
中文别名：
英文别名：4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzenecarbonitrile;UNII-TCN4MG2VXS;4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile;dapivirinum;Dapivirine (TMC120);Dapivirine;TMC120;
分子式：C20H19N5
分子量：329.398
精确质量：329.164
Psa：73.63
Logp：4.90668
中文别名：
英文别名：4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzenecarbonitrile;UNII-TCN4MG2VXS;4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile;dapivirinum;Dapivirine (TMC120);Dapivirine;TMC120;
分子式：C20H19N5
分子量：329.398
精确质量：329.164
Psa：73.63
Logp：4.90668
编号系统
MDL号：MFCD09833899
物化性质
密度：1.23g/cm3
沸点：557.9ºC at 760mmHg
闪点：291.2ºC
折射率：1.648
蒸汽压：1.76E-12mmHg at 25°C
沸点：557.9ºC at 760mmHg
闪点：291.2ºC
折射率：1.648
蒸汽压：1.76E-12mmHg at 25°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
