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  • 霉酚酸

    mycophenolic acid

化合物简介

An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.

基本信息

CAS:24280-93-1
中文别名:麦考酚酸;E-4-甲基-6-(1,3-二氢-7-甲基-4-羟基-6-甲氧基-3-氧代-5-异苯并呋喃基)-4-己烯酸;(E)-6-(1,3-二氢-4-羟基-6-甲氧基-7-甲基-3-氧代-5-异苯并呋喃基)-4-甲基l-4-己烯酸;
英文别名:4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-;Mycophenolinsure;mycophenolate;Mycophenolic acid;melbex;micofenolicoacido;Micophenolic acid;6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid;Mycophenolic;
分子式:C17H20O6
分子量:320.337
精确质量:320.126
Psa:93.06
Logp:2.7332

编号系统

MDL号:MFCD00036814
EINECS号:246-119-3
BRN号:1295848
PubChem号:24896987

物化性质

外观与性状:白色至灰白色粉末
密度:1.29 g/cm3
沸点:611.6ºC at 760 mmHg
熔点:141°C
闪点:225.8ºC
稳定性:Stable at normal temperatures and pressures.
储存条件:2-8ºC
蒸汽压:8.18E-16mmHg at 25°C

安全信息

RTECS号:MP8050000
安全说明:S53-S45
WGK Germany:3
危险类别码:R22
危险品运输编码:2811
海关编码:2932209090
危险类别:6.1(b)
包装等级:III
危险品标志:Xn
危险性防范说明:P201; P273; P281; P308 + P313; P501
危险性描述:H302; H341; H360D; H372; H410
危险标志:GHS07, GHS08, GHS09
信号词:Danger

生产方法及用途

用途
免疫抑制剂中间体。

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