化学科研者一站式服务平台
化合物简介
Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, and liquid aerosol. Tolnaftate is used to treat fungal conditions such as jock itch, athlete's foot and ringworm.
基本信息
CAS:2398-96-1
中文别名:N-甲基-N-(3-间甲苯基)硫代氨基甲酸-2-萘酯;
英文别名:Timoped;Tinactin;Tinavet;Dermoxin;sorgoa;Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester;Tritin;Tolnaftate;O-2-Naphthyl Methyl(3-methylphenyl)carbamothioate;Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthyl Ester;Pitrex;Aftate;Focusan;
分子式:C19H17NOS
分子量:307.409
精确质量:307.103
Psa:44.56
Logp:4.9483
中文别名:N-甲基-N-(3-间甲苯基)硫代氨基甲酸-2-萘酯;
英文别名:Timoped;Tinactin;Tinavet;Dermoxin;sorgoa;Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester;Tritin;Tolnaftate;O-2-Naphthyl Methyl(3-methylphenyl)carbamothioate;Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthyl Ester;Pitrex;Aftate;Focusan;
分子式:C19H17NOS
分子量:307.409
精确质量:307.103
Psa:44.56
Logp:4.9483
编号系统
MDL号:MFCD00056611
物化性质
外观与性状:白色粉末
密度:1.223 g/cm3
沸点:453.4ºC at 760 mmHg
熔点:110.5-111.5ºC
闪点:228ºC
折射率:1.697
储存条件:2-8ºC
蒸汽压:2.08E-08mmHg at 25°C
密度:1.223 g/cm3
沸点:453.4ºC at 760 mmHg
熔点:110.5-111.5ºC
闪点:228ºC
折射率:1.697
储存条件:2-8ºC
蒸汽压:2.08E-08mmHg at 25°C
安全信息
RTECS号:FD8891300
WGK Germany:2
海关编码:2930909090
WGK Germany:2
海关编码:2930909090
生产方法及用途
用途
局部抗真菌药。用于浅表皮肤真菌感染,包括体癣、股癣、手足癣、药斑癣、但对毛发部及指甲的真菌感染无效。
局部抗真菌药。用于浅表皮肤真菌感染,包括体癣、股癣、手足癣、药斑癣、但对毛发部及指甲的真菌感染无效。
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict

Mass spectrum (electron ionization)
