CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacological active acid product (CHR-79888) inside cells. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines in vitro and in vivo and shows selectivity for transformed over nontransformed cells. Its antiproliferative effects are at least 300 times more potent than the prototypical aminopeptidase inhibitor, Bestatin.

CAS：238750-77-1
中文别名：ALPHA-[[(2R)-2-[(1S)-1-羟基-2-(羟基氨基)-2-氧代乙基]-4-甲基-1-氧代戊基]氨基]苯乙酸环戊酯;他达拉非;
英文别名：cyclopentyl (2S)-2-[[(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl]amino]-2-phenylacetate;CHR2797-Tosedostat;CHR-2797;UNII-KZK563J2UW;
分子式：C21H30N2O6
分子量：406.473
精确质量：406.21
Psa：124.96
Logp：2.6401

密度：1.24
折射率：1.566