Methyl Thioglycolate is an derivative of Thioglycolic Acid, an organic compound containing both a thiol and a carboxylic acid functional groups. Thioglycolic Acid and its derivatives are often used in organic synthesis as a nucleophile in thioglycolysis reactions and is also used as a S transfer agent for sulfonyl chloride synthesis. Methyl Thioglycolate have been studied for the its influence on neocarzinostatin activation and expression of DNA damage.

CAS：2365-48-2
中文别名：硫代乙醇酸甲脂;硫代乙醇酸甲酯;
英文别名：methylthioglycolic ester;Thioglycolic Acid Methyl Ester;mercapto acetic acid methylester;2-mercaptoacetic acid methyl ester;USAF EK-7119;Methyl Thioglycolate;methyl mercaptoglycolate;methyl 2-mercaptoacetate;Acetic acid, mercapto-, methyl ester;Methanethiol,methoxy;Acetic acid,mercapto-,methyl ester;Mercaptoacetic Acid Methyl Ester;Methylthioglycolate;Thioglycolic acid methyl ester;Methyl mercaptoacetate;sulfanylacetic acid methyl ester;1-methoxycarbonylmethanethiol;
分子式：C3H6O2S
分子量：106.144
精确质量：106.009
Psa：65.1
Logp：0.0892

RTECS号：AI7350000
BRN号：506259
EINECS号：219-121-7
MDL号：MFCD00004873
PubChem号：24846848

外观与性状：无色或灰白的绿色液体
密度：1.187g/mLat 25°C(lit.)
沸点：42-43°C10mm Hg(lit.)
熔点：-24 °C
闪点：86°F
折射率：n20/D 1.466(lit.)
水溶解性：40 g/L (20 ºC)
稳定性：Stable under normal temperatures and pressures.
储存条件：Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
蒸汽压：3.58mmHg at 25°C

RTECS号：AI7350000
安全说明：S26-S36/37-S45-S36/37/39-S28A
危险类别码：R10; R20/22; R25; R36/37/38
WGK Germany：1
海关编码：29309070
危险品运输编码：UN 1992 3/PG 3
危险类别：3
包装等级：III
危险品标志：T; Xn
危险标志：GHS02, GHS06
信号词：Danger
危险性描述：H226; H301; H315; H319; H332; H335
危险性防范说明：P261; P301 + P310; P305 + P351 + P338

生产方法
其制备方法是在反应釜内加入巯基乙酸和甲醇,搅拌,滴加少量浓硫酸为催化剂,滴完,回流反应12h,反应结束后,加入水洗涤至中性,分水,得成品。 HSCH2COOH+CH3OH[H2SO4]→HSCH2COOCH3+H2O 医药及农药中间体。
用途
医药及农药中间体。