2-Methylphenylacetonitrile was used as a reactant to synthesize potential non-nucleoside reverse transcriptase inhibitors (NNRTIs) against HIV. It was also used to prepare derivatives of isoquinoline-1-carboxaldehyde thiosemicarbazone with antitumor activity.

CAS：22364-68-7
中文别名：2-甲基苯乙腈;邻甲苯乙腈;O-甲基苯腈;邻甲苯基乙腈;α-甲基苄腈;α-甲基苯乙腈;
英文别名：2-Methylbenzyl Cyanide;2-(o-Tolyl)acetonitrile;o-Xylyl cyanide;2-Methylphenylacetonitrile;2-Methylphenylacetonitrile 2-Methylbenzyl cyanide;2-methylbenzoacetonitrile;o-Xylyl Cyanide;2-Methylbenzyl cyanide;Benzeneacetonitrile, 2-methyl-;o-Methylbenzyl cyanide;o-Methylphenylacetonitrile;o-Tolylacetonitrile;
分子式：C9H9N
分子量：131.174
精确质量：131.073
Psa：23.79
Logp：2.06108

BRN号：907182
EINECS号：244-937-5
MDL号：MFCD00001904
RTECS号：AM2290000
PubChem号：24854036

外观与性状：淡黄色液体
密度：1.05
沸点：244-250 °C
熔点：58 - 59ºC
闪点：>110°C
折射率：1.5264-1.5284
稳定性：Stable under normal temperatures and pressures.
储存条件：Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
蒸汽压：4.52E-10mmHg at 25°C

RTECS号：AM2290000
安全说明：S36/37-S37/39-S27-S26
危险类别码：R20/21/22
海关编码：2926909090
危险品运输编码：3439
危险类别：6.1
包装等级：III
危险品标志：Xn

生产方法
用苯乙腈在碱性条件下与硫酸二甲酯反应制得。 氟比洛芬、吡咯芬的中间体
用途
氟比洛芬、吡咯芬的中间体