27-Hydroxycholesterol (27-HC) is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR). It is a metabolite of cholesterol that is produced by the enzyme CYP27A1.

CAS：20380-11-4
中文别名：27-羟基胆固醇;
英文别名：5,25R-Cholesten-3beta,26-diol;(25R)-cholest-5-ene-3beta,26-diol;
分子式：C27H46O2
分子量：402.653
精确质量：402.35
Psa：40.46
Logp：6.3611

UNII：6T2NA6P5SQ

密度：1.03
沸点：517.1ºC at 760 mmHg
熔点：172 - 173 °C
闪点：215.6ºC
折射率：1.537
蒸汽压：7.43E-13mmHg at 25°C