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化合物简介
N-Cbz-L-Leucine is an N-Cbz-protected form of L-Leucine. L-Leucine is an essential amino acid that induces a sharp decrease in blood glucose levels in individuals with idiopathic familial hypoglycemia, but has no known effects on normal, healthy individuals. L-Leucine also acts as an Isoleucine antagonist in the rat, causing delays in growth, and is a potential tumour promoter of bladder cancer.
基本信息
CAS:2018-66-8
中文别名:N-羧基-L-亮氨酸,CBZ-L-亮氨酸;苄氧羰基-L-亮氨酸;Cbz-L-亮氨酸;N-羧基-L-亮氨酸;Z-亮氨酸;Z-L-亮氨酸;
英文别名:Cbz-L-Leu-OH;Cbz-L-leucine;N-(Benzyloxycarbonyl)-L-leucine N-(B;N-(Benzyloxycarbonyl)-L-leucine (N-(Benzyloxycarbonyl)leucine;Z-L-Leucine;N-Carbobenzyloxy-L-leucine;Benzyloxycarbonylleucine;(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid;Carbobenzoxyleucine;(S)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoic acid;N-Carbobenzoxy-L-leucine;N-Cbz-L-leucine;N-Benzyloxycarbonyl-L-leucine;Z-Leu-OH;Benzyloxycarbonyl-L-leucine;
分子式:C14H19NO4
分子量:265.305
精确质量:265.131
Psa:75.63
Logp:2.803
中文别名:N-羧基-L-亮氨酸,CBZ-L-亮氨酸;苄氧羰基-L-亮氨酸;Cbz-L-亮氨酸;N-羧基-L-亮氨酸;Z-亮氨酸;Z-L-亮氨酸;
英文别名:Cbz-L-Leu-OH;Cbz-L-leucine;N-(Benzyloxycarbonyl)-L-leucine N-(B;N-(Benzyloxycarbonyl)-L-leucine (N-(Benzyloxycarbonyl)leucine;Z-L-Leucine;N-Carbobenzyloxy-L-leucine;Benzyloxycarbonylleucine;(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid;Carbobenzoxyleucine;(S)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoic acid;N-Carbobenzoxy-L-leucine;N-Cbz-L-leucine;N-Benzyloxycarbonyl-L-leucine;Z-Leu-OH;Benzyloxycarbonyl-L-leucine;
分子式:C14H19NO4
分子量:265.305
精确质量:265.131
Psa:75.63
Logp:2.803
编号系统
RTECS号:OH2921000
MDL号:MFCD00026494
PubChem号:24874197
BRN号:1253861
EINECS号:217-960-3
MDL号:MFCD00026494
PubChem号:24874197
BRN号:1253861
EINECS号:217-960-3
物化性质
外观与性状:黏的液体
密度:1g/mLat 25°C(lit.)
沸点:442.8ºC at 760 mmHg
闪点:85°F
折射率:n20/D 1.512(lit.)
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:2-8ºC
蒸汽压:1.28E-08mmHg at 25°C
密度:1g/mLat 25°C(lit.)
沸点:442.8ºC at 760 mmHg
闪点:85°F
折射率:n20/D 1.512(lit.)
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:2-8ºC
蒸汽压:1.28E-08mmHg at 25°C
安全信息
RTECS号:OH2921000
安全说明:S16-S26-S36/37/39-S45
危险类别码:R10; R20/22; R37/38; R40; R41
WGK Germany:3
海关编码:2924299090
危险品运输编码:UN 1993 3/PG 3
危险品标志:Xn
安全说明:S16-S26-S36/37/39-S45
危险类别码:R10; R20/22; R37/38; R40; R41
WGK Germany:3
海关编码:2924299090
危险品运输编码:UN 1993 3/PG 3
危险品标志:Xn
生产方法及用途
用途
用于生化试剂,缩宫素等多肽合成。
用于生化试剂,缩宫素等多肽合成。
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict

Raman : 4880 A,200 M,liquid

Mass

IR : liquid film

IR : CCl4 solution
