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化合物简介

Loxapine (several trade names worldwide) is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class and structurally related to clozapine (which belongs to the chemically akin class of dibenzodiazepines). Several researchers have argued that loxapine may behave as an atypical antipsychotic.

基本信息

CAS:1977-10-2
中文别名:克噻平;
英文别名:Loxapine;Dibenzoazepine;Loxapinum;Loxapina;Loxapin;Loxitane;8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine;Oxilapine;Cloxazepine;Dibenzacepin;Lossapina [DCIT];2-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine;2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine;
分子式:C18H18ClN3O
分子量:327.808
精确质量:327.114
Psa:28.07
Logp:3.0828

编号系统

UNII:LER583670J

物化性质

蒸汽压:1.36E-08mmHg at 25°C

安全信息

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


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