3,3'-Diindolylmethane is an activator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines. 3,3'-Diindolylmethane is an antiproliferative and inducer of apoptosis; promotes proteasomal degradation of Cdc25C and Cdk1. Inhibits phosphorylation of EGFR and downstream activation of ERK.

CAS：1968-05-4
中文别名：3,3’-二吲哚甲烷;二聚吲哚;3,3\'-亚甲基二吲哚;二(3,3\'-吲哚基)甲烷;
英文别名：3,3\'-Diindolymetane;Indolyl-CH2-Indolyl;3,3-Methylenediindole;3,3\'-Methylenebisindole；DIM;3,3\'-Methylenediindole;di(1H-indol-3-yl)methane;Diindole methane;DIM;HB 236;DI INDOLYL METHANE;3-(1H-indol-3-ylmethyl)-1H-indole;DI-3-INDOLYLMETHANE;3-DIINDOLYL METHANE;Di(1H-indol-3-yl)methane;3,3\'-methylene-bis(1H-indole);di-(1H-3-indolyl)methane;3,3\'-Diindolylmethane;ARUNDINE;Indole dimer;Di-3-indolylmethane;
分子式：C17H14N2
分子量：246.306
精确质量：246.116
Psa：31.58
Logp：4.24

RTECS号：NM0332000

外观与性状：白色结晶粉末
熔点：167 °C
蒸汽压：8.07E-10mmHg at 25°C

安全说明：S22; S24/25
海关编码：2933990090
危险性描述：H315; H319; H335; H413
信号词：Warning
危险性防范说明：P261; P305 + P351 + P338
危险标志：GHS07

用途
保健品及医药中间体。