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化合物简介
Mestilbol (brand name Monomestro or Monomestrol), also known as diethylstilbestrol monomethyl ether, is a synthetic, non-steroidal estrogen of the stilbestrol group related to diethylstilbestrol. It was developed by Wallace & Tiernan Company, patented in 1940, and introduced for medical use in the 1940s, but is now no longer marketed. Mestilbol was available both as oral tablets and in oil for intramuscular injection. The drug is gradually demethylated in the body into diethylstilbestrol and hence is a prodrug of diethylstilbestrol. Mestilbol is a highly active estrogen, although somewhat less so than diethylstilbestrol, but is longer-lasting in comparison.
基本信息
CAS:18839-90-2
中文别名:
英文别名:4-[1-Aethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol;(E)-4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-phenol;Monozol;4-[1-Aethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol;trans-4-(1-Ethyl-2-(4-(phenylmethoxy)phenyl)-1-butenyl)phenol;Pituitrope;Hypantin;Phenol, 4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-, (E)-;4-[1-ethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol;4-[1-ethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol;Stilbestrol monobenzyl ether;
分子式:C19H22O2
分子量:282.377
精确质量:282.162
Psa:29.46
Logp:5.1316
中文别名:
英文别名:4-[1-Aethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol;(E)-4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-phenol;Monozol;4-[1-Aethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol;trans-4-(1-Ethyl-2-(4-(phenylmethoxy)phenyl)-1-butenyl)phenol;Pituitrope;Hypantin;Phenol, 4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-, (E)-;4-[1-ethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol;4-[1-ethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol;Stilbestrol monobenzyl ether;
分子式:C19H22O2
分子量:282.377
精确质量:282.162
Psa:29.46
Logp:5.1316
编号系统
UNII:N44U12UW5N
物化性质
密度:1.054g/cm3
沸点:413.1ºC at 760mmHg
闪点:192.2ºC
折射率:1.571
蒸汽压:2.06E-07mmHg at 25°C
沸点:413.1ºC at 760mmHg
闪点:192.2ºC
折射率:1.571
蒸汽压:2.06E-07mmHg at 25°C
安全信息
海关编码:2909500000
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
