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  • (E)-4-(1-乙基-2-(4-甲氧基苯基)-1-丁烯基)苯酚

    4-[(3E)-4-(4-Methoxyphenyl)-3-hexen-3-yl]phenol

化合物简介

Mestilbol (brand name Monomestro or Monomestrol), also known as diethylstilbestrol monomethyl ether, is a synthetic, non-steroidal estrogen of the stilbestrol group related to diethylstilbestrol. It was developed by Wallace & Tiernan Company, patented in 1940, and introduced for medical use in the 1940s, but is now no longer marketed. Mestilbol was available both as oral tablets and in oil for intramuscular injection. The drug is gradually demethylated in the body into diethylstilbestrol and hence is a prodrug of diethylstilbestrol. Mestilbol is a highly active estrogen, although somewhat less so than diethylstilbestrol, but is longer-lasting in comparison.

基本信息

CAS:18839-90-2
中文别名
英文别名:4-[1-Aethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol;(E)-4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-phenol;Monozol;4-[1-Aethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol;trans-4-(1-Ethyl-2-(4-(phenylmethoxy)phenyl)-1-butenyl)phenol;Pituitrope;Hypantin;Phenol, 4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-, (E)-;4-[1-ethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol;4-[1-ethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol;Stilbestrol monobenzyl ether;
分子式:C19H22O2
分子量:282.377
精确质量:282.162
Psa:29.46
Logp:5.1316

编号系统

UNII:N44U12UW5N

物化性质

密度:1.054g/cm3
沸点:413.1ºC at 760mmHg
闪点:192.2ºC
折射率:1.571
蒸汽压:2.06E-07mmHg at 25°C

安全信息

海关编码:2909500000

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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