Phloxine B (commonly known simply as phloxine) is a water-soluble red dye used for coloring drugs and cosmetics in the United States and coloring food in Japan. It is derived from fluorescein, but differs by the presence of four bromine atoms at positions 2, 4, 5 and 7 of the xanthene ring and four chlorine atoms in the carboxyphenyl ring. It has an absorption maximum around 540 nm and an emission maximum around 564 nm. Apart from industrial use, phloxine B has functions as an antimicrobial substance, viability dye and biological stain. For example, it is used in hematoxylin-phloxine-saffron (HPS) staining to color the cytoplasm and connective tissue in shades of red.

CAS：18472-87-2
中文别名：红色28;荧光桃红B;焰火B;荧光桃红B,酸性红92;石南红;食品红104;酸性红92;
英文别名：AKA231;D and C Red No. 28;cred;EOSINE B;RED 28;D and C red dye No 28;red104;Food Red No. 104;SUREDYE;Phloxine B,high purity,Biological stain;Phloxine B disodium salt;PHLOXINE;2\',4\',5\',7\'-tetrabromo-4,5,6,7-tetrachlorofluorescein disodium salt;Red No. 28 Eosin 10B;Phloxine 92;
分子式：C20H2Br4Cl4Na2O5
分子量：829.634
精确质量：823.519
Psa：81.65
Logp：10.2058

RTECS号：LM5900000
BRN号：3887100
MDL号：MFCD00070627
PubChem号：24898359
EINECS号：242-355-6

外观与性状：红色至棕色粉末
沸点：747.3ºC at 760 mmHg
闪点：405.8ºC
稳定性：Stable. Incompatible with strong oxidizing agents.
储存条件：库房通风低温干燥,与氧化剂、酸类、食品添加剂分开存放
蒸汽压：1.85E-23mmHg at 25°C

RTECS号：LM5900000
安全说明：S22; S24/25; S37/39; S26
危险类别码：R36
WGK Germany：2
海关编码：32041200
危险品标志：Xi

生产方法
由间苯二酚与四氯酞酐缩合成四氯荧光素,再经溴化而得。 1.调色用橙红色素,日本广泛应用于糖果、糕点、鱼糕、香肠、糖食制品、饼干。不适用于pH值在4.5以下的饮料、硬糖等。用量5～100mg/kg。
用途
1.调色用橙红色素,日本广泛应用于糖果、糕点、鱼糕、香肠、糖食制品、饼干。不适用于pH值在4.5以下的饮料、硬糖等。用量5～100mg/kg。