AMG-3 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8THC substituted with a dithiolane group on the 3-position side chain. AMG-3 is a potent agonist at both CB1 and CB2 receptors with a Ki of 0.32nM at CB1 and 0.52nM at CB2, and its particularly high binding affinity has led to it being used as a template for further structural development of novel cannabinoid drugs. It has sedative and analgesic effects, with analgesia lasting for up to 36 hours after administration.

CAS：179044-94-1
中文别名：
英文别名：UNII-U90K6D923K;AMG 3;
分子式：C25H36O2S2
分子量：432.682
精确质量：432.216
Psa：80.06
Logp：7.6063

UNII：U90K6D923K