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Voreloxin
7-[(3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl]-4-oxo-1-(1,3-thiazol-2-yl)-1,8-naphthyridine-3-carboxylic acid
化合物简介
Vosaroxin (AG-7352, SPC-595, SNS 595, voreloxin) is a topoisomerase II inhibitor causing site-selective DNA damage.It is under phase III clinical trial investigation for acute myelogenous leukemia (AML) and ovarian cancer sponsored by Sunesis.
基本信息
CAS:175414-77-4
中文别名:VORELOXIN;
英文别名:CS-0790;AG 7352;Vosaroxin (USAN);Voreloxin (SNS-595);SNS-595;Voreloxin;vosaroxin;UNII-K6A90IIZ19;
分子式:C18H19N5O4S
分子量:401.44
精确质量:401.116
Psa:137.82
Logp:1.4193
中文别名:VORELOXIN;
英文别名:CS-0790;AG 7352;Vosaroxin (USAN);Voreloxin (SNS-595);SNS-595;Voreloxin;vosaroxin;UNII-K6A90IIZ19;
分子式:C18H19N5O4S
分子量:401.44
精确质量:401.116
Psa:137.82
Logp:1.4193
编号系统
UNII:K6A90IIZ19