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化合物简介
Bendamustine (INN, trade names Treakisym, Ribomustin, Levact and Treanda; also known as SDX-105) is a nitrogen mustard used in the treatment of chronic lymphocytic leukemia and lymphomas. It belongs to the family of drugs called alkylating agents. It is also being studied for the treatment of sarcoma. It is also being investigated in phase II trials for the non-cancer treatment of AL amyloidosis.
基本信息
CAS：16506-27-7
中文别名：4-[5-[双(2-氯乙基)氨基]-1-甲基苯并咪唑-2-基]丁酸;
英文别名：4-[5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl]butanoic acid;Bendamustina [Spanish];Bendamustin;4-{5-[bis-(2-chloro-ethyl)-amino]-1-methyl-1H-benzoimidazol-2-yl}-butyric acid;Bendamustinum [Latin];4-{5-[bis(2-chloroethyl)amino]-1-methyl-2-benzimidazolyl} butyric acid;UNII-9266D9P3PQ;Bendamustine (INN);SDX 105;4-<1-Methyl-5-benzimidazolyl-(2)>butansaeure;Treanda (TN);
分子式：C16H21Cl2N3O2
分子量：358.263
精确质量：357.101
Psa：58.36
Logp：3.2646
中文别名：4-[5-[双(2-氯乙基)氨基]-1-甲基苯并咪唑-2-基]丁酸;
英文别名：4-[5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl]butanoic acid;Bendamustina [Spanish];Bendamustin;4-{5-[bis-(2-chloro-ethyl)-amino]-1-methyl-1H-benzoimidazol-2-yl}-butyric acid;Bendamustinum [Latin];4-{5-[bis(2-chloroethyl)amino]-1-methyl-2-benzimidazolyl} butyric acid;UNII-9266D9P3PQ;Bendamustine (INN);SDX 105;4-<1-Methyl-5-
分子式：C16H21Cl2N3O2
分子量：358.263
精确质量：357.101
Psa：58.36
Logp：3.2646
编号系统
物化性质
密度：1.31 g/cm3
沸点：585.2ºC at 760 mmHg
折射率：1.599
蒸汽压：1.55E-14mmHg at 25°C
沸点：585.2ºC at 760 mmHg
折射率：1.599
蒸汽压：1.55E-14mmHg at 25°C
安全信息
海关编码：2933990090
生产方法及用途
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上游原料
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图谱
Predict 1H proton NMR
13C NMR : Predict
1H NMR : Predict
