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化合物简介
Vilazodone (United States trade name Viibryd VEYE-brid) is a serotonergic antidepressant developed by Clinical Data for the treatment of major depressive disorder. The chemical compound was originally developed by Merck KGaA (Germany). Vilazodone was approved by the FDA for use in the United States to treat major depressive disorder in 2011.
基本信息
CAS：163521-12-8
中文别名：维拉唑酮;
英文别名：5-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide;5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide;
分子式：C26H28ClN5O2
分子量：477.986
精确质量：477.193
Psa：102.29
Logp：5.53478
中文别名：维拉唑酮;
英文别名：5-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide;5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide;
分子式：C26H28ClN5O2
分子量：477.986
精确质量：477.193
Psa：102.29
Logp：5.53478
编号系统
MDL号：MFCD09838919
物化性质
外观与性状：淡黄色固体
密度：1.34 g/cm3
沸点：745.1ºC at 760 mmHg
熔点：203-205ºC
密度：1.34 g/cm3
沸点：745.1ºC at 760 mmHg
熔点：203-205ºC
安全信息
生产方法及用途
合成路线
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参考文献
DR.REDDYS LABORATORIES LIMITED; IQBAL, Javed; ORUGANTI, Srinivas; RAPOLU, Rajesh Kumar; PEDDY, Vishweshwar; BOGE, Rajesham; PATHIVADA, Deepika; VELAGA, Dharma Jagannadha Rao; YARRAGUNTLA, Sesha Reddy; BADDAM, Sudhakar Reddy; NAREDLA, Anitha; DONIPARTHI, Kiran Kumar; NADGOUD, Ramesh Kumar; PAGADALA, Narasimha Rao; UNNIARAN, Syam Kumar; RAMAKRISHNAN, Srividya Patent: WO2013/168126 A1, 2013 ; Location in patent: Page/Page column 75-78 ;
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
