HEPPS or EPPS are the common names for the compound 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic acid. It is used as a buffering agent in biology and biochemistry. The pKa of HEPPS is 8.00. Research on mice with Alzheimers disease-like [[Amyloid beta ]] plaques has shown that the EPPS can cause the plaques to break up, reversing some of the symptoms in the mice.

CAS：16052-06-5
中文别名：4-(2-羟乙基)-1-哌嗪丙磺酸(HEPPS);3-[4-(羟乙基)-1-哌嗪基]丙磺酸;N-2-羟乙基哌嗪-N’-3-丙磺酸;4-(2-羟乙基)-1-哌嗪丙磺酸;
英文别名：Hepps;3-(4-(2-Hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acid;3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic Acid;3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid;4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic Acid [Good\'s buffer component;EPPS;4-Hydroxyerhylpiperazine-1-propanesulfonic acid;
分子式：C9H20N2O4S
分子量：252.331
精确质量：252.114
Psa：89.46
Logp：-0.1692

MDL号：MFCD00006160
EINECS号：240-198-8
BRN号：3957385
PubChem号：24894443

外观与性状：白色结晶粉末
密度：1.285g/cm3
熔点：237-239°C(lit.)
折射率：1.537
稳定性：Stable under normal temperatures and pressures.
储存条件：Store at RT.

RTECS号：TM2649130
安全说明：S24/25
WGK Germany：3
危险类别码：R36/37/38
海关编码：29335995
危险品标志：Xi