化学科研者一站式服务平台


  • L-蛋氨酸亚砜亚胺

    L-methionine sulfoximine

化合物简介

Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).\n\nMethionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.

基本信息

CAS:15985-39-4
中文别名:L-S-(3-氨基-3-羧丙基)-S-甲基砜亚胺;L-蛋氨酸磺酸盐;L-蛋氨酸砜亚胺;
英文别名:(2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic acid;L-Methionine sulfoximine;L-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine;L-Methionine Sulfoximine;2-Amino-4-(S-methylsulfonimidoyl)butanoic acid;
分子式:C5H12N2O3S
分子量:180.225
精确质量:180.057
Psa:112.62
Logp:1.1307

编号系统

BRN号:6175446
MDL号:MFCD00002621
PubChem号:24278555

物化性质

外观与性状:白色结晶粉末
密度:1.46g/cm3
沸点:352.2ºC at 760mmHg
熔点:>210ºC (dec.)(lit.)
闪点:166.8ºC
储存条件:0-6ºC

安全信息

安全说明:S26
危险类别码:R36/37/38
海关编码:2925290090
危险品标志:Xi

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


加载中...