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6,8-二氟-1-(甲酰基甲基氨基)-7-(4-甲基-1-哌嗪基)-4-氧代-1,4-二氢喹啉-3-甲酸乙酯
ethyl 6,8-difluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1-(2-oxoethylamino)quinoline-3-carboxylate
化合物简介
6,8-Difluoro-1,4-dihydro-1-(N-methylformamido)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester is an intermediate in the synthesis of Marbofloxacin, a fluorinated quinolone antibacterial agent.
基本信息
CAS：158585-86-5
中文别名：6,8-二氟-1-(甲酰基甲基氨基)-7-(4-甲基哌嗪-1-基)-4-氧代-1,4-二氢喹啉-3-羧酸乙酯;
英文别名：I06-2622;Ethyl6,8-difluoro-1,4-dihydro-1-(N-methylformamido)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylate;ethyl 6,8-difluoro-1-(N-methylformamido)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate;3-Quinolinecarboxylicacid,6,8-difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-,ethyl ester;6,8-DIFLUORO-1-(FORMYLMETHYLAMINO)-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;6,8-difluoro-1-(N-methylformamido)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-quinoline-3-carboxylic acid ethyl ester;
分子式：C19H22F2N4O4
分子量：408.399
精确质量：408.161
Psa：83.88
Logp：1.0265
中文别名：6,8-二氟-1-(甲酰基甲基氨基)-7-(4-甲基哌嗪-1-基)-4-氧代-1,4-二氢喹啉-3-羧酸乙酯;
英文别名：I06-2622;Ethyl6,8-difluoro-1,4-dihydro-1-(N-methylformamido)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylate;ethyl 6,8-difluoro-1-(N-methylformamido)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate;3-Quinolinecarboxylicacid,6,8-difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-,ethyl ester;6,8-DIFLUORO-1-(FORMYLMETHYLAMINO)-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;6,8-difluoro-1-(N-methylformamido)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-quinoline-3-carboxylic acid ethyl ester;
分子式：C19H22F2N4O4
分子量：408.399
精确质量：408.161
Psa：83.88
Logp：1.0265
编号系统
EINECS号：605-155-3
物化性质
密度：1.41
沸点：543.7ºC at 760 mmHg
折射率：1.612
沸点：543.7ºC at 760 mmHg
折射率：1.612
安全信息
生产方法及用途
合成路线
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参考文献
US5892040 A1, ;
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
