Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. As such, it can be used in lab to bring about any of these effects. Specifically, butyrate treatment of cells results in histone hyperacetylation, and butyrate itself inhibits class I histone deacetylase (HDAC) activity, specifically HDAC1, HDAC2, HDAC3, and HDAC8. Butyrate has been an essential vehicle for determining the role of histone acetylation in chromatin structure and function. Inhibition of HDAC activity is estimated to affect the expression of only 2% of mammalian genes.

CAS：156-54-7
中文别名：丁酸钠盐;
英文别名：Natriumbutyrat;Butyrate sodium salt;BUTYRIC ACID NA;NAB;SODIUMBUTYRATE,USP;sodium n-butyrate;Sodium butanoate;SODIUM N-BUTYLATE;Sodium Butyrate;SODIUM BUTYRATE;Na butyrate;Sodium butyrate;SODIUM BUTYRATE pure;butyratesodium;butyric acid sodium salt;Butyric Acid Sodium Salt;
分子式：C4H7NaO2
分子量：110.087
精确质量：110.034
Psa：40.13
Logp：-0.4636

BRN号：3629439
PubChem号：5222465
EINECS号：205-857-6
MDL号：MFCD00002816
RTECS号：ET6400000

外观与性状：白色粉末
密度：0.987g/cm3
沸点：164.3ºC at 760 mmHg
熔点：250-253°C(lit.)
闪点：69.7ºC
水溶解性：soluble
稳定性：Stable. Incompatible with strong acids.
储存条件：库房低温,通风,干燥
蒸汽压：1.35mmHg at 25°C

RTECS号：ET6400000
安全说明：S37/39-S26-S24/25
WGK Germany：1
危险类别码：R36/37/38
海关编码：2915600000
危险品运输编码：2820
危险品标志：Xi
危险标志：GHS07
危险性描述：H315; H319; H335
信号词：Warning
危险性防范说明：P305 + P351 + P338

用途
广泛用于畜禽饲料添加中，可以提高采食量、饲料报酬和日增重。增强动物健康水平。减少腹泻和死亡率。