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化合物简介

Etoxazole is a narrow spectrum systemic acaricide used to combat spider mites. It targets a variety of mites in the egg, larvae and nymph stages however not the adult stage. It also exhibits insecticidal activity towards aphids, the green rice leafhopper and diamondback moth. The mode of action was originally suspected to inhibit the molting process but has since been shown to inhibit chitin synthesis. Resistance due to its high efficacy and cross resistance when used with other acaricides are both of concern similar to was seen in the fast development of cross resistance in the previous generation of acaricides. The LC50 for resistant mite strains has been observed over 100,000 times greater than that of susceptible strains. Thus resistance management strategies are important in order to limit the increase of etoxazole resistant mite strains.

基本信息

CAS:153233-91-1
中文别名:依杀螨;
英文别名:2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydrooxazole;rac-(4R)-2-(2,6-difluorophenyl)-4-(4-tert-butyl-2-ethoxyphenyl)-4,5-dihydro-1,3-oxazole;(RS)-5-tert-butyl-2-[2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazol-4-yl]phenetole;4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole;4-(4-tert-butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazole;
分子式:C21H23F2NO2
分子量:359.41
精确质量:359.17
Psa:30.82
Logp:4.6147

编号系统

MDL号:MFCD07363987

物化性质

密度:1.15g/cm3
沸点:449.1ºC at 760mmHg
熔点:101-102ºC
闪点:225.4ºC
折射率:1.537
储存条件:0-6ºC
蒸汽压:7.78E-08mmHg at 25°C

安全信息

安全说明:60-61
危险类别码:R50/53

生产方法及用途

用途
杀螨剂。

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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