化学科研者一站式服务平台

化合物简介

Cefalotin (INN) or cephalothin (USAN) is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed (1964) and continues to be widely used. It is an intravenously administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is marketed as Keflin (Lilly) and under other trade names.

基本信息

CAS:153-61-7
中文别名:头孢噻吩酸;
英文别名:Cefalotina;Cefalothin;Coaxin;Cefalotine;Cefalotinum;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cephalothinum;Cephalothin;Cemastin;Cefalotin;Cephalotin;
分子式:C16H16N2O6S2
分子量:396.438
精确质量:396.045
Psa:166.55
Logp:0.9211

编号系统

EINECS号:205-815-7

物化性质

外观与性状:白色晶体粉末
密度:1.56 g/cm3
沸点:757.2ºC at 760 mmHg
熔点:160-161ºC
闪点:411.8ºC
折射率:1.675
水溶解性:158 MG/L
储存条件:库房低温通风干燥
蒸汽压:4.25E-24mmHg at 25°C

安全信息

生产方法及用途

用途
抗菌素治疗各种感染。

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


加载中...