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盐酸阿齐利特
1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione,dihydrochloride
化合物简介
Azimilide Dihydrochloride is an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide also is being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction.
基本信息
CAS：149888-94-8
中文别名：
英文别名：azmilide;Azimilide hydrochloride;Stedicor;Azimilide HCl;Azimilide dihydrochloride;
分子式：C23H30Cl3N5O3
分子量：530.875
精确质量：529.141
Psa：72.6
Logp：4.5813
中文别名：
英文别名：azmilide;Azimilide hydrochloride;Stedicor;Azimilide HCl;Azimilide dihydrochloride;
分子式：C23H30Cl3N5O3
分子量：530.875
精确质量：529.141
Psa：72.6
Logp：4.5813
编号系统
物化性质
密度：1.32g/cm3
沸点：594.9ºC at 760mmHg
闪点：313.6ºC
沸点：594.9ºC at 760mmHg
闪点：313.6ºC
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
