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化合物简介
H1 Histamine receptor antagonist. Antihistaminic.
基本信息
CAS:14976-57-9
中文别名:阿扎胞苷;(R-(R*,R*))-1-甲基-2-(2-(1-(4-氯苯基)-1-苯乙氧基)乙基)-吡咯烷 (E)-2-丁烯二酸盐;阿扎胞苷.氮杂胞苷;
英文别名:(+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt;Clemastine Fumarate;Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-, (E)-2-butenedioate (1:1);Clemastine fumarate;Pyrrolidine (2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl;Clemastine fumarate salt;Tavist,Agasten;
分子式:C25H30ClNO5
分子量:459.962
精确质量:459.181
Psa:87.07
Logp:4.7541
中文别名:阿扎胞苷;(R-(R*,R*))-1-甲基-2-(2-(1-(4-氯苯基)-1-苯乙氧基)乙基)-吡咯烷 (E)-2-丁烯二酸盐;阿扎胞苷.氮杂胞苷;
英文别名:(+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt;Clemastine Fumarate;Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-, (E)-2-butenedioate (1:1);Clemastine fumarate;Pyrrolidine (2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl;Clemastine fumarate salt;Tavist,Agasten;
分子式:C25H30ClNO5
分子量:459.962
精确质量:459.181
Psa:87.07
Logp:4.7541
编号系统
MDL号:MFCD00137486
RTECS号:UY0704600
EINECS号:239-055-2
PubChem号:24278344
RTECS号:UY0704600
EINECS号:239-055-2
PubChem号:24278344
物化性质
外观与性状:白色或近乎于白色结晶粉末
密度:1.097 g/cm3
沸点:116 °C / 24mmHg
熔点:61 °C
闪点:211ºC
折射率:1.553
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:1.94E-07mmHg at 25°C
密度:1.097 g/cm3
沸点:116 °C / 24mmHg
熔点:61 °C
闪点:211ºC
折射率:1.553
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:1.94E-07mmHg at 25°C
安全信息
RTECS号:UY0704600
海关编码:2933990090
海关编码:2933990090
生产方法及用途
用途
作用及抗过敏药。
作用及抗过敏药。
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict

Mass

IR : nujol mull

IR : KBr disc
