Patulin is a mycotoxin produced by a variety of molds, in particular, Aspergillus and Penicillium and Byssochlamys. Most commonly found in rotting apples, in general the amount of patulin in apple products is viewed as a measure of the quality of the apples used in production. In addition, patulin has been found in other foods such as grains, fruits, and vegetables. While not considered a particularly potent toxin, a number of studies have shown patulin to be genotoxic, which has led some to theorize that it may be a carcinogen, although animal studies have remained inconclusive. Patulin has shown antimicrobial properties against some microorganisms. Several countries have instituted patulin restrictions in apple products. The World Health Organization recommends a maximum concentration of 50µg/L in apple juice. In the European Union, the limit is set to 50 micrograms per kilogram (µg/kg) in both apple juice and cider, and to half of that concentration, 25µg/kg, in solid apple products and 10µg/kg in products for infants and young children. These limits came into force on 1 November 2003.

CAS：149-29-1
中文别名：开放毒霉素;4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮;
英文别名：Leucopin;Clavatin;Expansine;4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one,PAT;Patuline;Clavacin;Gigantin;Claviform;Expansin;Clairformin;4-hydroxy-4,6-dihydrofuro[3,2-c]pyran-2-one;4H-Furo[3,2-c]pyran-2(6H)-one, 4-hydroxy-;
分子式：C7H6O4
分子量：154.12
精确质量：154.027
Psa：55.76
Logp：-0.2979

PubChem号：24898227
BRN号：149675
EINECS号：205-735-2
MDL号：MFCD00005858
RTECS号：LV2625000

外观与性状：白色结晶
密度：1.52 g/cm3
沸点：513.7ºC at 760 mmHg
熔点：108-111 °C
闪点：226.8ºC
折射率：1.603
储存条件：库房低温,通风,干燥,与食品原料分开存放
蒸汽压：1.06E-12mmHg at 25°C

RTECS号：LV2625000
安全说明：S45-S36/37
WGK Germany：3
危险类别码：R25
危险品运输编码：UN 3462 6.1/PG 2
危险类别：6.1(a)
包装等级：I
危险品标志：T; Xn

生产方法
由青霉菌属中许多不同的种发酵所产生 广谱抗细菌、抗真菌抗生素，并有抗肿瘤作用。对猫有利尿作用。由于对人、动物(小鼠LD50静脉注射25～35mg/kg)和植物(1μg/
用途
广谱抗细菌、抗真菌抗生素，并有抗肿瘤作用。对猫有利尿作用。由于对人、动物(小鼠LD50静脉注射25～35mg/kg)和植物(1μg/